Small-World Networks and RNA Secondary Structures
نویسندگان
چکیده
منابع مشابه
Relation Between RNA Sequences, Structures, and Shapes via Variation Networks
Background: RNA plays key role in many aspects of biological processes and its tertiary structure is critical for its biological function. RNA secondary structure represents various significant portions of RNA tertiary structure. Since the biological function of RNA is concluded indirectly from its primary structure, it would be important to analyze the relations between the RNA sequences and t...
متن کاملNeutral Networks of Interacting RNA Secondary Structures
RNA molecules interact by forming inter-molecular base pairs that compete with the intramolecular base pairs of their secondary structures. Here we investigate the patterns of neutral mutations in RNAs whose function is the interaction with other RNAs, i.e., of co-folding RNAs. We find that (1) the degree of neutrality is much smaller in interacting RNAs compared to RNAs that just have to cofor...
متن کاملrelation between rna sequences, structures, and shapes via variation networks
background: rna plays key role in many aspects of biological processes and its tertiary structure is critical for its biological function. rna secondary structure represents various significant portions of rna tertiary structure. since the biological function of rna is concluded indirectly from its primary structure, it would be important to analyze the relations between the rna sequences and t...
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Background: Knowing the development pattern of children’s language is applicable in developmental psychology. Network models of language are helpful for the identification of these patterns. Objectives: We examined the small-world properties of featured semantic networks of developing children. Materials & Methods: In this longitudinal study, the featured semantic networks of children aged 1...
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A class of wedge-shaped small molecules has been designed, synthesized, and shown to bind bulged RNA secondary structures. These minimally cationic ligands exhibit good affinity and selectivity for certain RNA bulges as demonstrated in a fluorescent intercalator displacement assay.
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2019
ISSN: 1557-8666
DOI: 10.1089/cmb.2018.0125